Cell Line Derived Tumor Xenograft (cdx) Mouse Models

vAs a vital step in the process of antineoplastic agent discovery, cell line derived tumor xenograft (CDX) models are widely used for preclinical test of drug efficacy, PK/PD correlation, and combination therapy. Human tumor cell line xenografts establish tumors when implanted in immunodeficient mouse. In this kind of model, it's feasible to investigate the efficacy of novel agents in inhibiting tumor growth and development as well as the mechanisms of action. https://www.creative-biolabs.com/drug-discovery/therapeutics/cell-line-derived-tumor-xenograft-cdx-mouse-models.htm